prepGEM Universal is the core of the Exymes range: a single-tube extraction kit suitable for cell culture, blood, saliva, solid tissue, hair, and tape lifts.

It performs particularly well with low cell-number samples, where extraction yield scales linearly with cell count and where conventional methods introduce unacceptable loss.

For CRISPR/Cas9 genotyping workflows, where speed and 100% DNA recovery matter, it has become a useful tool for labs that previously relied on Proteinase K-based methods.

A head-to-head comparison of prepGEM versus Proteinase K is available as application note EXAPN018.